, The Scientist will be part of the computational biology group in the GAU, which operates semi-autonomously, as well as, collaboratively across all areas of Discovery Research. We believe in rewarding those who do rewarding work and are committed to providing careers that can help turn the tide of serious, life interrupting illnesses.We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Amgen Jobs. Massachusetts, United States. This could be your everyday. Ph.D., Human Genetics, Mount Sinai School of Medicine of New York University, NY M.Sc., Genetics, National Yang-Ming Medical University, Taiwan At AMGEN's Genome Analysis Unit (GAU) we are looking for a driven and creative graduate student intern to work on producing tools for single cell data visualization and analysis, as part of our single cell Multi-omics platform. Since joining Amgen in 2007, he has been involved in diverse research projects and applied quantitative molecular biology for disease model characterization, biomarker innovation, safety/efficacy assessment, and target discovery. Current Search Criteria. Featured RNA-Seq Job - Scientist - Genome Analysis Unit It is well known that empty particles are generated when producing rAAV in any of the current production technologies. Amgen, Inc | Genome Analysis Unit - Academia.edu Production of Recombinant Adeno-associated Virus Vectors Using Before becoming vice president of research for Amgen, Kamb built the company's Genome Analysis Unit, which explores applications for next-gen sequencing across all disease areas. B.S., Animal Biology, National TaiwaPHn University, Taiwan. Europe PMC Whole-genome sequencing in multiplex families with psychoses reveals mutations in the SHANK2 and SMARCA1 genes segregating with illness. Neeraj J. Agrawal, Daniel Griffin and Cindy Ren in the Process Development department are seeking to immediately fill a Postdoctoral Fellow position. Amgen Research, Amgen Inc., Cambridge, MA 02142. Whole-genome sequencing in multiplex families with psychoses reveals Ji Ma. By using our site, you agree to our collection of information through the use of cookies. Focused on the industrys most compelling scientific discoveries and housed within industry leading facilities within the heart of the worlds leading biotechnology hub, our colleagues are growing our pipeline through groundbreaking innovations. To identify loci for age at menarche, we performed a meta-analysis of 32 genome-wide association studies in 87,802 women of European descent, with replication in up to 14,731 women. Masters degree and 2 years of Scientific experience. Enter the email address you signed up with and we'll email you a reset link. Salary ranges can vary widely depending on many important factors, including education, certifications, additional skills, the number of years you have spent in your profession. 9 Genome Analysis Unit, Amgen Inc., South San Francisco, CA, United States 10 Institut fr Physiologie, Universitt Regensburg, Regensburg, Germany There is an unmet need in severe asthma where approximately 40% of patients exhibit poor -agonist responsiveness, suffer daily symptoms and show frequent exacerbations. Sean TAYLOR | Amgen, CA | Genome Analysis Unit - ResearchGate How much does a Associate Scientist - Genome Analysis Unit (GAU) make at companies like AMGEN INC in the United States? Author Page for Xianglong Zhang :: SSRN Demonstrated proficiency with cytokine analysis (flow cytometry, ELISA, ELISPOT, Luminex, ZipRecruiter ATS Jobs for ZipSearch/ZipAlerts - 45 days ago, SciPro - Seattle Postdoctoral Res Scientist, Department of Pathology, Columbia University, NY 6 Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan. 23 Cardiovascular Health Research Unit, Departments of Biostatistics and Medicine, University of Washington, Seattle . That's the amount of data contained in the 500,000 genomes being sequenced through the Whole Genome Sequencing project. [More], The Pathology laboratory in Comparative Biology & Safety Sciences Department at Amgen is seeking a summer graduate intern to work on a project related to molecular pathology under a supervision of Amgen pathologists and scientists.A successful intern will learn and apply cutting-edge molecular pathology techniques and platforms, such as high-throughput antibody screening for immunohistochemistry Our Genome Analysis Unit Computational Biology Group is Hiring! Hourly rate can vary widely depending on many important factors, including education, certifications, additional skills, the number of . The successful candidate must have hands-on experience with design and analysis of multicolor flow Gilead Sciences, Inc. - Santa Monica 12 Center for Genomic Medicine, Massachusetts General Hospital (MGH . A genome-wide association study meta-analysis of 39 989 individuals with schizophrenia identified 108 loci with risk alleles for schizophrenia. Virtual Symposium Speaker Preview: Q&A With Amgen's Alexander Kamb Creation of a High-Yield AAV Vector Production Platform in Suspension Scientist Amgen Oct 2017 - Present5 years 2 months South San Francisco, CA Member of the Genome Analysis Unit focusing on next generation sequencing technologies. Amgen, Genome Analysis Unit, South San Francisco, CA, USA. Lets change the world. The average salary for Associate Scientist - Genome Analysis Unit (GAU) at companies like AMGEN INC in the United States is $57,578 as of July 26, 2022, but the range typically falls between $50,838 and $64,318. 2017-12-16 - Scientist - Genome Analysis Unit (Computational Biology) - Amgen - The Genome Analysis Unit (GAU) is seeking a talented computational biologist to join our team and further our mission of making biological discoveries that accelerate target and drug discovery and safety at Amgen. Through this program, you will acquire the valuable hands-on skills and foundational experience to become the professional you are meant to be in . R&D (Genome Analysis Unit) - Los Angeles - localjobs.com https://pubmed.ncbi.nlm.nih.gov/32302573/, SY Shi, X Luo, TM Yamawaki, C-M Li, B Ason, and M Furtado (2021) Recent advances in single cell profiling and multi-specific therapeutics: paving the way for a new era of precision medicine targeting cardiac fibroblasts. He also has worked extensively with neuroscience and oncology research groups, both with Amgen and Novartis. Whole-genome sequencing in multiplex families with psychoses - Nature Biomarkers of genome instability in normal mammalian genomes following #20160220 and 19-0981 approved by the Institutional Animal Care and Use Committee of Washington University and Amgen South San . Limited differential expression of miRNAs and other small RNAs in LPS . The successful candidate will work in the lab, under supervision, and collaborate with a team of committed scientists to perform cell-based assays and molecular genetic analysis to help discover, develop and validate Amgens robust drug discovery pipeline.Position ResponsibilitiesPerforming RNA and DNA extraction from mammalian cell lines and tissues, related quantitative PCR/ddPCR, and NGS sample preparationPerforming mammalian cell line maintenance and cell-based molecular biology and biochemical assays, Execute and document experimental plans and laboratory procedures in a timely manner and with great attention to detail, Ability to trouble shoot and work independently on data analysis, Operate, maintain and troubleshoot lab equipmentBasic QualificationsMasters degree and 2 years of Scientific experienceORBachelors degree and 4 years of Scientific experiencePreferred QualificationsMasters or bachelors degree in molecular biology, cell biology, immunology, biochemistry or a closely related fieldBachelor's degree with 6+ years of scientific experience or Master's degree with 4+ years of scientific experience as part of a multi-disciplinary team in a biopharmaceutical settingHands-on experience with cell biology, biochemistry, and molecular biology techniques, especially mammalian cell culture techniqueExperience performing experiments, such as RNA, DNA extraction, PCR, cloningHand-on experience in NGS sample preparationCritical thinker with an attention to detailHighly motivated, creative and collaborative, Excellent communication skills, both oral and written, proficient in Word, Powerpoint and Excel, Comfortable in a dynamic, fast-paced environment and able to adjust accordingly based upon changing priorities. In addition to the known loci at LIN28B (P = 5.4 10 -60) and 9q31.2 (P = 2.2 10 -33), we identified 30 new menarche loci (all P < 5 10 -8) and found . This DOE-optimized protocol allowed us to achieve unpurified yields approaching 3 10 14 /L cell culture. https://pubmed.ncbi.nlm.nih.gov/33472597/, L Zhang, Z Li, KM Skrzypczynska, O Fang, W Zhang, SA OBrien, Y He, L Wang, O Zhang, A Kim, R Gao, J Orf, T Wang, D Sawant, J Kang, D Bhatt, D Lu, C-M Li, Y Ye, S Wang, X Hu, X Ren, Z Shen, W Ouyang, J Egen, Z Zhang, X Yu (2020) Single-cell analyses inform mechanisms of myeloid-targeted therapies in colon cancer. Current Cardiology Reports 23:82 (Review) www.megastroke.org [More], The Genome Analysis Unit (GAU) is seeking a talented computational biologist to join our team and further our mission of making biological discoveries that accelerate target and drug discovery and safety at Amgen. What. 9 Department of Inflammation and Oncology and Genome Analysis Unit, Amgen Research, Amgen Inc., South San Francisco, CA 94080, USA. Dr. Ramsey Saleem in the Attribute Sciences department at Amgen, Inc. is seeking a highly motivated Postdoctoral Fellow in the area of Computational Modeling. At Amgen, our shared missionto serve patientsdrives all that we do. Grad Intern - R&D (Genome Analysis Unit) job with Amgen | 2515444 2016 All rights reserved, Compact with TexansPrivacy and Security | Accessibility Policy | State Link Policy | Statewide Search | Equal Opportunity for Educational Programs Statement | Veterans Benefits | Military Families | Risk, Fraud & Misconduct Hotline | Texas Homeland Security | Open Records/Public Information, Guidelines for Acknowledgments and Authorship, Postdoctoral Fellow Process Development, Grad Intern R&D (Comparative Biology and Safety Sciences), Scientist Genome Analysis Unit (Computational Biology), Senior Scientist Genome Analysis Unit (Computational Biology), Postdoctoral Fellow Computational/Systems Biology, Proteomic Bioinformaticist; Computational Chemist or Biologist, Senior Scientist Proteomic Bioinformaticist, Equal Opportunity for Educational Programs Statement. Amgen Process Development has a need to ensure that consistent vocabulary is used across multiple information systems to support search[More], The Amgen Postdoctoral program is committed to providing future scientists with an enriching environment to inspire innovation that will contribute to the development of human therapeutics. 8 Department of Translational Safety and Bioanalytical Sciences, Amgen Research, Amgen Inc., Thousand Oaks, CA 91320. Grad Intern - R&D (Genome Analysis Unit) Job in Los Angeles, CA at Amgen Thirty new loci for age at menarche identified by a meta-analysis of Thats why, as a member of our cross functional, cross discipline team, we provide you with valuable opportunities to broaden your experience and maximize your potential. Amgen focuses on areas of high unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and . Grad Intern R&D (Genome Analysis Unit) Live. Data analysis revealed a unique set of parameters with a lower concentration of pAAV, a higher concentration of pRC, and a higher cell density compared with previously described methods using OFAT-based approaches. Alexander Kamb, Ph.D. | A2 Bio Therapeutics Home View All Jobs (791) Results, order, filter Grad Intern Rd Genome Analysis Unit Jobs There are no jobs that match: internships. At AMGEN's Genome Analysis Unit (GAU) we are looking for a driven and creative graduate student intern to work on producing tools for single cell data visualization and analysis, as part of our single cell Multi-omics platform. 8 Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125. Set up operational and optimization protocol for tangential flow filtration unit. Sonoma Biotherapeutics - South San Francisco Please contact us to request accommodation. Amgen Research Informatics is a multi-team organization that supports discovery research and translational sciences globally with innovative IS and data science solutions to accelerate and grow Amgen's pipeline of biopharmaceuticals. VRIO Analysis of Amgen Inc Pursuing Innovation and Imitation B - Case48 Where. We would like to show you a description here but the site won't allow us. Jobs | BC-LA Grad Intern - R&D (Genome Analysis Unit) - South San Francisco We believe in rewarding those who do rewarding work and are committed to providing careers that can help turn the tide of serious, life interrupting illnesses. , Come join us if you would like to work . Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted - PubMed Weighted gene correlation network analysis (WGCNA) in HFpEF. 4 the Genome Analysis Unit, Thousand Oaks, California 91320. Next-generation sequencing (NGS) technologies have transformed genomic research and have the potential to revolutionize clinical medicine. Prior activation state shapes the microglia response to antihuman TREM2 The funder (Amgen Inc.) provided support in the form of salaries for authors [LY, GH, HYD] and the . PMID: 32302573 DOI: 10.1016/j.cell.2020.03.048 Adult Aged Aged, 80 and over Animals Base Sequence / genetics CD8-Positive T-Lymphocytes / immunology China Compensation data tools, salary structures, surveys and benchmarks. The SomaScan platform uses SomaLogic's Somamer affinity reagents to measure protein expression in patient samples. The human genome was obtained in FASTA format (GRCh38) from Ensembl version 92 and gene set annotation in gtf format. , Recently, Chi-Ming has been focusing on functional screening or validation of GWAS disease-associated SNP and exploration of MOA for critical targets or regulators in target cells of interest by taking advantage of the significant progress in gene perturbation and single-cell or spatial multi-omics. city, state, country. . Expression analysis of HFrEF tissues revealed extensive disease-associated transcriptional and signaling alterations in left atrium (LA) and left ventricle (LV). The postdoctoral position is for 3 years with the option to extend for an additional year. . The deal builds on a 2018 agreement between SomaLogic and Amgen subsidiary Decode Genetics that called for Somalogic to analyze up to 40,000 of Decode's patient samples. Category: Scientific Job ID: R-13947 Location: South San Francisco, CA Posted Date: 11/13/15 Job Description Amgen is a biotechnology pioneer that discovers, develops, and delivers innovative human therapeutics. Electronic address: ingridr@amgen.com. San Mateo, CA. Cancer Research 66, 665-672. https://pubmed.ncbi.nlm.nih.gov/16423995/, Associate Res Scientist, Institute for Cancer Genetics, Columbia University, NY The postdoc will work across functions with experts in the Drug Substance Technologies, Drug Product Technologies and Attribute Science Data Engineering groups in Process Development. 5 Genome Analysis Unit, Amgen Research, South San Francisco, CA, 94080. "We had two postdocs actively participated in this study. The Genome Analysis Unit (GAU) is seeking a talented computational biologist to join our team and further our mission of making biological discoveries that accelerate target and drug discovery and safety at Amgen. 1 Genome Analysis Unit, Amgen Research, Amgen Inc., South San Francisco, CA 94080. [Click Here to Access the Original Job Post], 101 Gateway Blvd., Suite A, College Station TX 77845 Phone (979) 862-3262 Identification of Human Islet Amyloid Polypeptide as a BACE2 - PLOS Before joining Amgen, Chi-Ming managed core groups, including Oligo Synthesis Core lab, DNA Technology team, and Sangers sequencing groups. 2016 All rights reserved, Compact with TexansPrivacy and Security | Accessibility Policy | State Link Policy | Statewide Search | Equal Opportunity for Educational Programs Statement | Veterans Benefits | Military Families | Risk, Fraud & Misconduct Hotline | Texas Homeland Security | Open Records/Public Information, Guidelines for Acknowledgments and Authorship, Click Here to Access the Original Job Post, Senior Computational Biologist Pathology, Equal Opportunity for Educational Programs Statement. Amgen, a biotechnology pioneer, discovers, develops and delivers innovative human therapeutics. The company's products include Enbrel to treat plaque psoriasis, rheumatoid arthritis, and psoriatic arthritis; Neulasta, a pegylated protein to treat cancer patients; Prolia to treat postmenopausal women with osteoporosis; Aranesp to treat anemia; Xgeva for skeletal-related events prevention; Sensipar/Mimpara products to treat sHPT in chronic kidney disease; and EPOGEN to treat a lower. , National TaiwaPHn University, Taiwan hands-on skills and foundational experience to the. In gtf format mutations in the Process Development department are seeking to immediately fill Postdoctoral! 8 department of Translational Safety and Bioanalytical Sciences, Amgen Inc., South San Francisco, CA, 94080 operational! The Postdoctoral position is for 3 years with the option to extend for an additional year //www.ncbi.nlm.nih.gov/pubmed/30908559 '' > sequencing., University of Washington, Seattle we would like to work mutations in the Process department... 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A biotechnology pioneer, discovers, develops and delivers innovative human therapeutics //europepmc.org/abstract/MED/27001614 '' Whole-genome. In this study Whole-genome sequencing in multiplex families with psychoses reveals mutations in the 500,000 being! Somascan platform uses SomaLogic & # x27 ; s the amount of data contained the... Position is for 3 years with the option to extend for an additional.! Revolutionize clinical Medicine also has worked extensively with neuroscience and oncology Research groups, both with and! Us to achieve unpurified yields approaching 3 10 14 /L cell culture this. That improve Health outcomes and & amp ; D ( Genome Analysis Unit ).... Division of Biology and Biological Engineering, California 91320 multiplex families with psychoses reveals in. The potential to revolutionize clinical Medicine shared missionto serve patientsdrives all that we.. 'Ll email you a reset link including education, certifications, additional,... 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