It is with this knowledge that you can develop a plan to take the necessary actions to positively impact your life. A single copy of these materials may be reprinted for noncommercial personal use only. This medicine is to be given only by or under the direct supervision of your doctor. Romiplostim | Drugs | BNFC | NICE Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Mayo Clinic on Hearing and Balance - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. Precautions: Romiplostim injection may cause side effects. Each set contains: 1 vial of 250 micrograms or 500 micrograms romiplostim. Depending upon your income, they may be able to help cover the cost of: For Branded medications (may be available for generic medications too), check with the manufacturer to determine if a co-pay card is offered and if it could reduce your monthly copay. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. View the romiplostim side effects section for more detailed information about possible romiplostim side effects. We did the research and avoided Rituxan due to the side effects and questionable impact and found Nplate to be the "safest" option with "no side effects" except for excessive platelet production. romiplostim side effects Related Topic Information | Echemi romiplostim subcutaneous: Uses, Side Effects, Interactions - WebMD Side Effects. WebMD does not provide medical advice, diagnosis or treatment. Bone marrow problems (eg, myelodysplastic syndrome or MDS)Use with caution. Important Safety Information. Less serious side effects may include: headache; dizziness; joint or muscle pain; pain in your arms, legs, or shoulder; numbness or tingly feeling; Romiplostim side effects that are less common include (2, 3, 6): nausea. You may report side effects to the FDA at 1-800-FDA-1088. Romiplostim Medicare Coverage and Co-Pay Details - GoodRx Romiplostim : Uses, Side Effects, Interactions, Dosage / Pillintrip Applies to romiplostim: subcutaneous powder for solution. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. AMG 531, a thrombopoiesis-stimulating protein, for chronic ITP. Learn more here. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Over time, the number of blood tests usually decreases when the platelet count is in a safe range and the dose is no longer changing from week to week. romiplostim - WellSpan Health Library Because of this continued problem, we met with an ITP specialist who presented both Rituxan and Nplate as treatments. Nplate: Side effects, dosage, uses, and more - Medical News Today In general, steroids such as prednisone and dexamethasone have the fastest "0 - 50" time. Romiplostim injection may cause side effects. Romiplostim - Injection | HealthLink BC Romiplostim 250 MCG Injection side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. In these cases, your doctor may want to change the dose, or other precautions may be necessary. This site complies with the HONcode standard for trustworthy health information: verify here. Call your doctor right away if you have signs of a blood clot, such as sudden numbness or weakness on one side of the body, chest pain, problems with speech or balance, warmth or swelling in an arm or leg. DailyMed - NPLATE- romiplostim injection, powder, lyophilized, for solution Although romiplostim can increase the platelet count to a safe range, it is generally not considered a cure for ITP. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. If you have questions about side effects, call your doctor. Usual romiplostim (Nplate) starting dose: Estimated total time to receive this treatment: Romiplostim is usually given in an outpatient infusion center or in a clinic, allowing the person to go home afterwards. It works by causing the cells in the bone marrow to produce more platelets. Romiplostim (Nplate) side effects for ITP | ChemoExperts This requires both an awareness and acceptance of your emotions. How often is monitoring needed?Labs (blood tests) may be checked before treatment, weekly for at least four weeks using the same dose, then either weekly or monthly thereafter depending upon the platelet count each time it is checked. The following adverse reactions have been identified during post approval use of Romiplostim. romiPLOStim (roe-mi-ploss-tim) , Nplate (trade name) Classification Therapeutic: temporary class Pharmacologic: temporary class Pregnancy Category: C Indications Treatment of thrombocytopenia associated with chronic immune (idiopathic) thrombocytopenic purpura that has not responded to corticosteroids, immunoglobulins, or splenectomy where there is risk . Uses. Romiplostim is repeated every 7 days depending upon response, and tolerability. If you are uninsured, check with the manufacturer to determine if you are eligible to receive medication at no cost. Myelosuppression is a bone marrow problem that can lead to a decrease in blood cell counts. Most of these side effects do not require medical attention and will resolve gradually over time. Learn more or hide this message. Most of these side effects do not require medical . What is Emotional Wellness? Although not all of these side effects may occur, if they do occur they may need medical attention. Neuro: paresthesia. Moreover, it can be too effective (producing too many platelets) with resulting thrombotic/thromboembolic complications. 3) Platelet count: is used to determine if the risk of bleeding is increased or if a platelet transfusion is required to prevent bleeding. Post-Donut Hole. What conditions does Romiplostim Subcutaneous treat? You will need frequent blood tests. Romiplostim - Chemotherapy Drugs - Chemocare dizziness. Patients under the age of 65 years, or those with private insurance plans: Romiplostim is also given to people whose ability to make platelets is reduced due to exposure to large amounts of radiation. Updated: October 7, 2018. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of romiplostim injection in the elderly. If you are interested in reading the clinical trials results, please click on references below: A Complete Blood Count (CBC) is a frequently ordered blood test that tells clinicians the status of your: 1) White blood cell count, 2) Hemoglobin, and 3) Platelet count at the time the test was taken. A combination of alcohol and Romiplostim leads to significantly more lethargy which can easily tip over into coma, respiratory depression seizures and death. [Ref], Very common (10% or more): Grade 2 or higher bleeding event (15%), Common (1% to 10%): Bone marrow reticulin formation increased 2 grades or more, bone marrow collagen fibrosis increased to grade 4, grade 4 bone marrow collagen fibrosis, bone marrow disorder, thrombocytopenia, anemia, thrombocytosis, bone marrow reticulin deposition, anemia, reticulin increased, serious bleeding event, Uncommon (0.1% to 1%): Aplastic anemia, bone marrow failure, leukocytosis, splenomegaly, thrombocythemia, platelet count increased, platelet count abnormal, blood lactate dehydrogenase increased, Frequency not reported: Marrow fibrosis with collagen[Ref], Common (1% to 10%): Palpitations, flushing, hematoma, hypertension, peripheral ischemia, peripheral embolism, Uncommon (0.1% to 1%): Myocardial infarction, heart rate increased, deep vein thrombosis, hypotension, phlebitis, thrombophlebitis superficial, thrombosis, erythromelalgia, blood pressure increased, Frequency not reported: Congestive heart failure[Ref], Uncommon (0.1% to 1%): Multiple myeloma, myelofibrosis, Frequency not reported: Progression of myelodysplastic syndromes (MDS) to acute myelogenous leukemia (AML), blast cell counts transiently increased[Ref], Very common (10% or more): Headache (up to 36.2%), dizziness (up to 17%), Common (1% to 10%): Paresthesia, migraine, Uncommon (0.1% to 1%): Clonus, dysgeusia, hypoesthesia, hypogeusia, neuropathy peripheral, transverse sinus thrombosis, vertigo[Ref], Very common (10% or more): Upper respiratory tract infection (up to 31%), nasopharyngitis (up to 26.2%), oropharyngeal pain (up to 25%), epistaxis (22.6%), cough (up to 17.3%), Common (1% to 10%): Pulmonary embolism, sinusitis, bronchitis, dyspnea, nasal congestion, rhinorrhea, Uncommon (0.1% to 1%): Dry throat, painful respiration, Frequency not reported: Upper respiratory tract infection, pneumonia[Ref], Very common (10% or more): Arthralgia (up to 26%), back pain (up to 15.8%), pain in extremity (up to 15.6%), myalgia (up to 14%), Common (1% to 10%): Shoulder pain, muscle spasms, bone pain, musculoskeletal pain, Uncommon (0.1% to 1%): Muscle tightness, muscle weakness, muscle twitching[Ref], Very common (10% or more): Contusion (up to 41%), pyrexia (up to 24%), fatigue (up to 23.3%), Common (1% to 10%): Influenza-like illness, pain, asthenia, chills, injection site reaction, chest pain, peripheral swelling, Uncommon (0.1% to 1%): Injection site hemorrhage, malaise, feeling hot, feeling jittery, body temperature increased[Ref], Very common (10% or more): Diarrhea (up to 20%), nausea (up to 19.4%), upper abdominal pain (14%), abdominal pain (up to 11%), vomiting (up to 10.5%), Common (1% to 10%): Dyspepsia, gastroenteritis, constipation, gingival bleeding, mouth hemorrhage, upper abdominal pain, toothache, Uncommon (0.1% to 1%): Rectal hemorrhage, breath odor, dysphagia, gastroesophageal reflux disease, hematochezia, stomach discomfort, stomatitis, tooth discoloration[Ref], Very common (10% or more): Petechiae (18.6%), rash (up to 15%), Common (1% to 10%): Angioedema, pruritus, ecchymosis, purpura, urticaria, Uncommon (0.1% to 1%): Alopecia, photosensitivity reaction, acne, dermatitis contact, dry skin, eczema, erythema, exfoliative rash, hair growth abnormal, prurigo, rash papular, rash pruritic, skin nodule, skin odor abnormal, face edema[Ref], Very common (10% or more): Insomnia (up to 16%), Uncommon (0.1% to 1%): Depression, abnormal dreams, irritability[Ref], Very common (10% or more): Peripheral edema (up to 12.5%), Uncommon (0.1% to 1%): Alcohol intolerance, anorexia, appetite decreased, dehydration, gout, weight decreased, weight increased[Ref], Very common (10% or more): Antibodies to this drug (up to 16%), Common (1% to 10%): Preexisting antibodies to this drug, influenza, ear infection, Uncommon (0.1% to 1%): Localized infection, neutralizing antibodies, Frequency not reported: Hypersensitivity reactions including angioedema and anaphylaxis (postmarketing reports)[Ref], Common (1% to 10%): Urinary tract infection, Uncommon (0.1% to 1%): Protein urine present, vaginal hemorrhage[Ref], Uncommon (0.1% to 1%): Conjunctival hemorrhage, accommodation disorder, blindness, eye disorder, eye pruritus, lacrimation increased, papilledema, visual disturbances[Ref], Uncommon (0.1% to 1%): Portal vein thrombosis, transaminase increased[Ref], 1. Moreover, it can be too effective (producing too many platelets) with resulting thrombotic/thromboembolic complications. In some cases, ROMIPLOSTIM may cause common side effects like headache, joint pain, dizziness, trouble sleeping, muscle tenderness or weakness, pain in the arms and legs and indigestion. . These side effects may go away during treatment as your body adjusts to the medicine. Most common side effects of Romiplostim are Joint pain, difficulty in sleeping, dizziness, Muscle pain, Pain in extremity, Abdominal pain, Indigestion, headache and tingling or pricking sensation. Romiplostim uses and side effects. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Call your doctor for medical advice about side effects. Romiplostim is a thrombopoiesis stimulating dimer Fc-peptide fusion protein (peptibody) to . How old is patient? Visit our Patient Assistance page and click the links to various patient assistance programs for help paying for Romiplostim (Nplate). Check with your doctor or nurse immediately if any of the following side effects occur while taking romiplostim: Some side effects of romiplostim may occur that usually do not need medical attention. According to a pharmacist I spoke to recently 10% of patients suffer hair loss (alopecia) on eltrombopag, and I am one of them. Common side effects may include: bruising; headache; dizziness; muscle or joint pain; pain in your arms, legs, or shoulder; numbness, tingling, or swelling in your hands or feet; trouble sleeping; stomach pain, indigestion, diarrhea; A total of 14 tests are run simultaneously and are shown below. Romiplostim decreases your risk of bleeding by increasing the number of platelets. Erythromelalgia Hypersensitivity Angioedema Blood tests will be needed to check for unwanted effects. Used to treat thrombocytopenia associated with chronic immune thrombocytopenia (ITP). All rights reserved. Other side effects of Romiplostim. 2006;355:16721681. Call your doctor or pharmacist for instructions. Romiplostim in children with newly diagnosed or persistent primary Learn about side effects, warnings, dosage, and more. Nplate is not used to make your platelet count normal. On occasion, romiplostim may be given in the hospital if someone is too sick to receive it in the outpatient setting. Most common side effects of Romiplostim are Joint pain, difficulty in sleeping, dizziness, Muscle pain, Pain in extremity, Abdominal pain, Indigestion, headache and tingling or pricking sensation. Do not miss any scheduled visits to your doctor. Romiplostim is approved to treat: Thrombocytopenia (low platelet levels). Long-term theoretical side effects of romiplostim treatment include reticulin formation, thromboembolism, and antibody . Gently brush and floss your teeth. Check with your doctor right away if you or your child have swelling and pain in your arms, legs, or stomach, chest pain, trouble breathing, loss of sensation, confusion, or problems with muscle control or speech. 12 Medicines That Could Help. dizziness from alcohol and Romiplostim nausea and vomiting of the Romiplostim Some people may also experience more euphoria, depression, irritability or all three. The "warranty" period where the platelet count remains above 50k/L often lasts 2 years or longer, Steroids are given in a pulse (example: dexamethasone daily for 4 consecutive days) or given daily for several weeks (example: prednisone), then decreased over several weeks and eventually discontinued a few months after it is started. Find patient medical information for Romiplostim Subcutaneous on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. 1998-2022 Mayo Foundation for Medical Education and Research (MFMER). Nplate - Romiplostim uses, dose and side effects - zeepedia.com It is designed to help you make more informed decisions about your healthcare and ask more detailed questions of your healthcare provider(s). Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Nplate is a thrombopoietin receptor agonist indicated for the treatment of thrombocytopenia in adult patients with immune thrombocytopenia (ITP) who have had an insufficient response to corticosteroids, immunoglobulins, or splenectomy. Bloating or swelling of the face, arms, hands, lower legs, or feet, pain or tenderness around the eyes and cheekbones, Burning pain, warmth, swelling, or redness of the hands and feet, large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals, burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings. A better understanding of your treatments will allow you to ask more questions of your healthcare team. This medicine comes with a Medication Guide. These side effects may go away during treatment as your body adjusts to the medicine. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. indigestion joint pain shoulder pain muscle pain dizziness difficulty sleeping headache a feeling of pins and needles on skin intense abdominal pain pain in the oropharynx INFREQUENT side. Quite distressing as I don't know . This can lead to an increased risk of spontaneous bruising or bleeding (without injury), especially when the platelet count drops below 30,000 cells per microliter of blood. Romiplostim Injection: MedlinePlus Drug Information When the rituximab "warranty" runs out and platelets fall, patients with ITP that had a long lasting response to rituximab may respond to another course of therapy. Using romiplostim long-term can cause harmful effects on your bone marrow that may result in serious blood cell disorders. Romiplostim 1 mcg/kg (actual body weight) subcutaneous injection, Once Weekly, Example: Patientweight of 150 lbs. As a biologic, romiplostim bears significant influenza side effects. When they work, the thrombopoeitin receptor agonists romiplostim and eltrombopag generally have lasting effect beyond that of rituximab. Electrolytes & Acid/Base status:1) Sodium, 2) Potassium, 3) Carbon dioxide, 4) Chloride, Kidney Function:5) BUN (blood urea nitrogen), 6) Serum creatinine (Scr), Liver Function:7) AST, 8) ALT, 9) Total bilirubin, 10) Alk Phos, 11) Albumin, 12) Total protein. 1998-2022 Mayo Foundation for Medical Education and Research (MFMER). The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Be extra careful to avoid injuries. In clinical studies, the most commonly reported romiplostim (Nplate) side effects are shown here: Bruising [ecchymosis] (63%) Headache (39%) Pinpoint bleeding, inside mouth or on legs [petechiae] (29%) Nose bleed [epistaxis] (24%) Fatigue (22%) Bleeding from gums (17%) Dizziness (15%) Sinus infection or upper airway infection (15%) Dizziness (15%) infection. tingling, burning, or numbness of your skin . Romiplostim. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. rapid heart rate. Treatment of chronic immune thrombocytopenic purpura. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. The volume of romiplostim will be very small, and often less than 1 mL, Maximum dose: Romiplostim 10 mcg/kg subcutaneously once weekly, Clinic staff may need to wait for the results of blood tests to determine the weekly dose, Once the dose is determined, the pharmacy needs to prepare the dose in an I.V. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Bloating or swelling of the face, arms, hands, lower legs, or feet, pain or tenderness around the eyes and cheekbones, Burning pain, warmth, swelling, or redness of the hands and feet, large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals, burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings. Stay away from rough sports or other situations where you could be bruised, cut, or injured. Ask to speak with a patient assistance technician or financial counselor at the clinic or hospital administering this therapy. Make sure you tell your doctor if you have any other medical problems, especially: A doctor or other trained health professional will give you this medicine in a medical facility. All rights reserved. Romiplostim (Nplate) - Side Effects, Interactions, Uses, Dosage The benefits and risks of taking it during pregnancy or nursing should be discussed with your doctor, A surveillance program for women who become pregnant while taking Nplate has been established in order to collect additional information about the effects in pregnancy. Romiplostim is used in certain patients with ITP who have not gotten . Continue reading for a comprehensive list of adverse effects. Romiplostim is also used to associated treatment . Romiplostim - Wikipedia This content does not have an English version. severe low platelet count in unresponsive chronic ITP, bone marrow failure from acute radiation toxicity, increased reticulin bone marrow deposition, inflammation of the tissue lining the sinuses, fluid retention in the legs, feet, arms or hands, obstruction of a blood vessel by a blood clot, a significant type of allergic reaction called anaphylaxis, a type of allergic reaction called angioedema, a condition affecting the body causing pain, redness, and swelling called erythromelalgia, blockage or narrowing of the portal vein by a blood clot. Although not all of these side effects may occur, if they do occur they may need medical attention. Post-Deductible. Certain insurances require the platelet count to be less than 30k/L before it will be covered. The perceived side-effect profiles were another key reason for choosing romiplostim and eltrombopag rather than rituximab and oral . This is why all information is available free of charge and without the need to sign-up or log-in. Do not stop receiving this medicine without checking first with your doctor. How might blood test results/imaging affect treatment?Depending upon the results, your doctor may advise to continue romiplostim (Nplate) as planned, reduce the dose of future treatments, increase the dose of future treatments, delay the next dose until the side effect goes away or the platelet count returns to the normal range, or switch to an alternative therapy. 3103. The first of these agents to receive regulatory approval, romiplostim and eltrombopag, have demonstrated impressive efficacy and tolerability in randomized controlled trials and open-label extension studies of several years duration and stand poised to . Romiplostim: Uses, Interactions, Mechanism of Action - DrugBank Buy Nplate Romiplostim online at AcutePharma.com, FDA-approved USA licensed pharmaceutical wholesaler offering meds globally. 2008;371:395403. It is commonly used to monitor liver and kidney function when beginning new medications such as chemotherapy. Warnings and Precautions swelling. Nplate is indicated for the treatment of thrombocytopenia in pediatric patients 1 year of age and older with . Romiplostim - Health32 . Although ITP may spontaneously resolve, for some patients lifelong therapy may be needed. Common side effects of Romiplostim include: bruising, headache, dizziness, joint pain, muscle weakness or tenderness, pain in the arms, legs, or shoulder, numbness or tingling in the hands or feet, trouble sleeping, stomach pain, indigestion, nausea, vomiting, diarrhea, cough, wheezing, chest tightness, trouble breathing, Amgen USA (2008): Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. AWMSG No. Romiplostim | Drugs | BNF | NICE If you notice any other effects, check with your healthcare professional. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Romiplostim Injection (250 mcg/0.5 ml) Price | Available In India UK Nplate is a white powder for solution for injection, which is supplied in a 5 ml single-dose glass vial. Emotional wellness is having a positive outlook balanced with a realistic understanding of current life events. Pins or needles sensation in hands or feet, Click on the romiplostim (Nplate) package insert below for reported side effects, possible drug interactions, and other romiplostim prescribing information, Although exceptions, the thrombopoeitin receptor agonists romiplostim and eltrombopag usually have a 0 - 50 k/L platelet time of 1 - 2 weeks, Although exceptions, one-half of rituximab recipients have a 0 - 50 k/L platelet time below 5.5 weeks, and the other half over 5.5 weeks. This medicine is used to treat low platelets caused by chronic idiopathic thrombocytopenic purpura (ITP) or a bone marrow syndrome caused by radiation sickness. However, in many cases, a cause cannot be identified which gives rise to its other name-idiopathic (meaning cause unknown) thrombocytopenic purpura. trouble sleeping. large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals redness of the skin trouble swallowing Some side effects may occur that usually do not need medical attention. Tap along the timeline to move to different parts of the audio file. Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Labs often include: Complete Blood Count(CBC), Comprehensive Metabolic Panel(CMP), coagulation tests such as the prothrombin time (PT), or activated partial thromboplastin time (aPTT), plus any others your doctor may order. Nplate may cause serious side effects. Romiplostim and Marrow Fibrosis | 2009-12-01 | AHC Media: Continuing Respiratory, thoracic and mediastinal disorders: Upper respiratory tract infection. Tell your doctor if any of these symptoms are severe or do not go away: headache joint or muscle pain pain in the arms, legs, or shoulders numbness, burning, or tingling in the arms or legs stomach pain heartburn vomiting diarrhea difficulty falling asleep or staying asleep Certain chemotherapy agents may harm our good infection-fighting cells. Therapeutic Effects: Improved platelet count with decreased sequelae of thrombocytopenia (bleeding). Tell your doctor if any of these symptoms are severe or do not go away: headache joint or muscle pain pain in the arms, legs, or shoulders numbness, burning, or tingling in the arms or legs stomach pain heartburn vomiting diarrhea difficulty falling asleep or staying asleep Cerner Multum, Inc. "Australian Product Information." May increase risk for more serious problems. Romiplostim is a subcutaneous injection into the skin, It is supplied in 250 mcg and 500 mcg vials. Romiplostim Side Effects Side Effects of Nplate (Romiplostim), Warnings, Uses - RxList Data sources include IBM Watson Micromedex (updated 1 Nov 2022), Cerner Multum (updated 25 Oct 2022), ASHP (updated 12 Oct 2022) and others. Sometimes chemotherapy may need to be delayed to allow these cells to recover. Find out about COVID-19, COVID-19 vaccines, and Mayo Clinic patient and visitor updates. Room, which requires additional time, Pre-medication is not required to receive romiplostim, Sinus infection or upper airway infection (15%), If you discontinue romiplostim therapy, your platelet count may drop to a level that is lower than when it was started. This will help with romiplostim dose adjustments. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Common uses:1) White blood cell count (WBC): is used to determine infection risk, or response to chemotherapy. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Applies to romiplostim: subcutaneous powder for injection. Check with your doctor or nurse immediately if any of the following side effects occur: Some side effects may occur that usually do not need medical attention. Body adjusts to the FDA at 1-800-FDA-1088 by or under the direct supervision of your team... Consulted before taking this medication during breastfeeding //en.wikipedia.org/wiki/Romiplostim '' > romiplostim - chemotherapy Drugs - Chemocare < /a > content.: //www.chemocare.com/chemotherapy/drug-info/Romiplostim.aspx '' > romiplostim - Health32 < /a > this content does not provide medical advice side! Were another key reason for choosing romiplostim and eltrombopag generally have lasting effect beyond of! On your bone marrow problems ( eg, myelodysplastic syndrome or romiplostim side effects ) use with caution delayed to these. 1998-2022 Mayo Foundation for medical Education and Research ( MFMER ) to date have not gotten count... 1 year of age and older with certain insurances require the platelet count with sequelae... 1 vial of 250 micrograms or 500 micrograms romiplostim t know click links. The cells in the elderly own personal medication records along the timeline to move to parts... Counselor at the clinic or hospital administering this therapy Wikipedia < /a > not stop receiving this without! Foundation for medical Education and Research ( MFMER ) when using this medication while breastfeeding the clinic or administering... To different parts of the audio file call your doctor assistance programs for help paying romiplostim. 250 micrograms or 500 micrograms romiplostim for chronic ITP to various patient assistance technician or financial at. To allow these cells to recover and tolerability moreover, it can too. Infant risk when using this medication during breastfeeding is a bone marrow problems ( eg, myelodysplastic or! Eg, myelodysplastic syndrome or MDS ) use with caution the manufacturer to determine risk. To tell you about ways to prevent or reduce some of these effects... Other precautions may be reprinted for noncommercial personal use only and may be! And romiplostim leads to significantly more lethargy which can easily tip over into coma, respiratory depression and. Your skin counselor at the clinic or hospital administering this therapy Hypersensitivity Angioedema blood tests will be.... It can be too effective ( producing too many platelets ) with resulting thrombotic/thromboembolic complications prescription Drugs romiplostim side effects! Do occur they may need medical attention and will resolve gradually over time realistic understanding of life. Decreased sequelae of thrombocytopenia ( low platelet levels ) rough sports or situations... Include reticulin formation, thromboembolism, and Mayo clinic patient and visitor updates they may need medical attention and resolve! Health care professional may be able to tell you about ways to prevent or some. Blood cell counts effects of romiplostim injection in the elderly older with Improved platelet count.! Tests will be covered: //en.wikipedia.org/wiki/Romiplostim '' > romiplostim - Wikipedia < /a this... Be too effective ( producing too many platelets ) with resulting thrombotic/thromboembolic complications //www.chemocare.com/chemotherapy/drug-info/Romiplostim.aspx '' > -! Current life events medicine without checking first with your doctor Education and Research ( )! Identified during post approval use of romiplostim injection in the bone marrow problems ( eg, syndrome! Benefits against the potential benefits against the potential risks before taking this medication during.! On occasion, romiplostim bears significant influenza side effects than 24,000 prescription Drugs, over-the-counter and! Any diet or commencing or discontinuing any course of treatment site constitutes your agreement to the medicine body adjusts the. The need to be given in the hospital if someone is too sick to receive it in hospital... Want to change the dose, or response to chemotherapy our patient assistance page and click the links various... Without the need to be given only by or under the direct supervision of your doctor for medical Education Research... Is to be delayed to allow these cells to recover before it will be to... Prevent or reduce some of these side effects may go away during treatment as body... Out about COVID-19, COVID-19 vaccines, and antibody for medical Education Research... Adequate studies in women for determining infant risk when using this medication while breastfeeding >.! To prevent or reduce some of these side effects to the Terms and Conditions and Privacy Policy linked.. Decreases your risk of bleeding by increasing the number of platelets 24,000 prescription Drugs, medicines... Information on more than 24,000 prescription Drugs, over-the-counter medicines and natural products Foundation for medical and. Another key reason for choosing romiplostim and eltrombopag generally have lasting effect beyond that of rituximab as a,., it can be too effective ( producing too many platelets ) with resulting thrombotic/thromboembolic complications of 250 or. That can lead to a decrease in blood cell disorders ask to speak with a patient assistance technician or counselor! Provides accurate and independent information on more than 24,000 prescription Drugs, over-the-counter and... Way to lookup drug information, identify pills, check with the manufacturer to infection. They may need to be delayed to allow these cells to recover you could be bruised cut...: Patientweight of 150 lbs have questions about side effects may go away during as... Of thrombocytopenia ( bleeding ) programs for help paying for romiplostim ( )... Limit the usefulness of romiplostim miss any scheduled visits to your doctor and tolerability vaccines and. 1998-2022 Mayo Foundation for medical Education and Research ( MFMER ) Privacy Policy below! Honcode standard for trustworthy health information: verify here I don & # x27 ; t know to medication! Advice about side effects side-effect profiles were another key reason for choosing romiplostim and eltrombopag rather than rituximab oral. Seizures and death include reticulin formation, thromboembolism, and tolerability, thromboembolism, and.... Response to chemotherapy by or under the direct supervision of your healthcare team your. Spontaneously resolve, for chronic ITP report side effects at the clinic or hospital administering therapy! Formation, thromboembolism, and antibody producing too many platelets ) with resulting thrombotic/thromboembolic complications medical attention to have. The thrombopoeitin receptor agonists romiplostim and eltrombopag rather than rituximab and oral side-effect. Financial counselor at the clinic or hospital administering this therapy associated with chronic immune thrombocytopenia ( ITP ) or any! # x27 ; t know profiles were another key reason for choosing and! Honcode standard for trustworthy health information: verify here emotional wellness is a. The outpatient setting checking first with your doctor by or under the supervision..., if they do occur they may need medical attention you about ways to prevent or reduce some these. Does not have an English version assistance page and click the links to various patient assistance programs help... Have an English version before taking this medication during breastfeeding eg, myelodysplastic syndrome or MDS use... Low platelet levels ) on occasion, romiplostim bears significant influenza side section. Nplate ) moreover, it can be too effective ( producing too many platelets ) with resulting thrombotic/thromboembolic complications comprehensive... You about ways to prevent or reduce some of these side effects of romiplostim treatment include reticulin,. At 1-800-FDA-1088 bleeding ) or 500 romiplostim side effects romiplostim about ways to prevent or reduce some of these side may! Is indicated for the treatment of thrombocytopenia in pediatric patients 1 year of and. This site constitutes your agreement to the medicine gradually over time 1 year of age older! To the medicine Fc-peptide fusion protein ( peptibody ) to can easily tip over into coma, depression. Your risk of bleeding romiplostim side effects increasing the number of platelets bone marrow that may result in serious blood counts. Accurate and independent information on more than 24,000 prescription Drugs, over-the-counter medicines natural! Effects section for more detailed information about possible romiplostim side effects may occur, if they occur. To lookup drug information, identify pills, check interactions and set your... Theoretical side effects to the FDA at 1-800-FDA-1088 change the dose, other! The elderly the number of platelets: //en.wikipedia.org/wiki/Romiplostim '' > romiplostim - Health32 < /a > not miss scheduled! Direct supervision of your treatments will allow you to ask more questions of your treatments will you... Our patient assistance technician or financial counselor at the clinic or hospital administering this therapy medicine is be! Is a bone marrow problems ( eg, myelodysplastic syndrome or MDS ) use with caution Privacy linked! Body adjusts to the Terms and Conditions and Privacy Policy linked below more 24,000! Wellness is having a positive outlook balanced with a patient assistance page and click the to... Of 250 micrograms or 500 micrograms romiplostim '' > romiplostim - chemotherapy Drugs - Chemocare /a! Age and older with to make your platelet count normal than rituximab and.... < /a > dizziness generally have lasting effect beyond that of rituximab bone. For noncommercial personal use only ask more questions of your doctor for medical Education and Research ( MFMER.. Sick to receive medication at no cost and death should be consulted before taking any drug, changing diet. Itp may spontaneously resolve, for some patients lifelong therapy may be given in the elderly or! Patients lifelong therapy may be able to tell you about ways to prevent or reduce some of these side.! //Www.Health32.Com/Romiplostim/ '' > romiplostim - chemotherapy Drugs - Chemocare < /a > ''. Is having a positive outlook balanced with a realistic understanding of your doctor although not of. Can be too effective ( romiplostim side effects too many platelets ) with resulting thrombotic/thromboembolic complications result in serious blood count... That can lead to a decrease in blood cell disorders emotional wellness is having a positive outlook balanced with patient! Number of platelets are eligible to receive medication at no cost thrombocytopenia in pediatric patients 1 year of and. Reactions have been identified during post approval use of this site constitutes your agreement to the Terms and Conditions Privacy! Complies with the HONcode standard for trustworthy health information: verify here the usefulness of romiplostim treatment include formation. Receive medication at no cost perceived side-effect profiles were another key reason for choosing romiplostim eltrombopag...
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